Cancer therapy has already entered the era of precision medicine.

Precision medicine is used to perform genetic testing before the patient undergoes cancer therapy. Through genetic testing, physicians are armed with the gene mutation information and are able to formulate suitable treatment strategies, accurately select medications, and adjust dosages to reduce side effects to achieve better treatment results. This is also called personalized medicine.

Patients afflicted by the same cancer type may have different gene mutations and need to be treated with different therapies. For instance, in the past, the gene most commonly identified in lung cancer patients was EGFR (epidermal growth factor receptor), which is related to the growth, differentiation, aggressiveness and survival of cancer cells; in recent years, ALK (anaplastic lymphoma kinase) gene has also been identified. Only through genetic testing we have the opportunity to identify the various pathogenic genes with relation to lung cancer and block them, thus creating the environment to inhibit the continuous deterioration caused by tumor.

At present, samples for genetic testing of solid tumors can be derived from pathological sections and liquid biopsy. Pathological section is derived from the tumor tissue and is the basis of most clinical evidence; the liquid biopsy is drawn from blood as an alternative when the tissue is not easy to obtain. Nowadays, most international treatment guidelines still recommend pathological section, and liquid biopsy is recommended only as an alternative.

There are 30,000 genes in the 23 pairs of chromosomes in the human body, which are composed of about 3 billion bases (nucleotides), and there is only 0.1% difference between people, which creates different appearances, physiological functions, personalities and even health risks. Genes affect about one-third of human health, and the other two-thirds are related to other factors such as environment, diet, and behaviors. Genetic testing allows us to understand in advance the weaker parts of the body and the risk of disease, and then, with the help of doctors, guide the individual in promoting a healthy life style. To put it simply, predictive genetic testing service is using genetic information of the human body to find the source of the disease affecting our current physical condition and predict the possibility of developing diseases in the future.

Infectious diseases are a major category of diseases that seriously threaten human health in the world today. Infectious diseases are mostly local or systemic inflammation or organ dysfunction caused by pathogens such as bacteria, viruses and fungi and their products, are more harmful and have a higher mortality rate. At present, the global incidence of infectious diseases has increased, and pathogens are showing a trend of diversification and developing complexity. Severe acute respiratory syndrome (SARS), new coronavirus infection (SARS-CoV-2), H7N9 and H10N8 virus avian influenza and other newly discovered infectious diseases keep emerging. Classical infectious disease pathogens such as HIV, multi- or broad-spectrum drug-resistant Mycobacterium tuberculosis, and Chlamydia trachomatis have revived or have developed new pathogenic characteristics. All kinds of new and recurring infectious diseases, multiple infections that are not easy to identify, and fever of unknown etiology, all pose a huge threat to human health.

Traditional microbial diagnosis methods have limitations, and it is difficult to quickly and accurately identify infectious pathogenic microorganisms. The Leopard Gene Next Generation pathogenic testing applies the principal of Metagenomic Next Generation Sequencing (mNGS) technology to detect DNA viruses in 7,098 species of bacteria, 8,717 species of viruses, 618 species of parasites, 8,521 species of fungi, 305 species of archaea and other pathogenic microorganisms, drug resistance genes and virulence factors. Precise screening and identification of pathogenic microorganisms are important tools for the differential diagnosis, treatment and medication of fever and bacteremia of unknown origin.

According to statistics on the causes of death announced by the Ministry of Health and Welfare, Taiwan in 2019, heart disease, cerebrovascular disease and hypertensive disease ranked second, fourth, and eighth place respectively. The occurrence of cardiovascular disease is mostly sudden, because most cardiovascular diseases do not have any warning signs, but once cardiovascular diseases occur, it will often cause death or irreversible damage, causing a huge burden to the family, and is a silent and dangerous health killer. Although cardiovascular diseases are related to aging, changes in diet and life styles can decrease the occurrence of cardiovascular disease at a young age.

According to research statistics, 90% of cardiovascular diseases can be prevented by reducing risk factors such as high blood pressure, diabetes, diet, exercise, smoking, and alcohol consumption. Although age, gender, genes and family history cannot be changed, the genes associated with cardiovascular disorders can be screened through genetic testing to be aware of our own physical characteristics and practice early prevention measures to drastically reduce the incidence of the disease.

Leopard Gene applies next-generation sequencing to analyze genes related to inherited heart diseases and screen patients for related pathogenic mutations. It can help physicians determine the diagnosis, evaluate the prognosis, give appropriate treatment, medication, and follow up properly.

Clinical diagnosis of neurological diseases rely on detailed neurological examinations, assessment of mental state, family history, and the use of imaging technologies (computer tomography or MRI) to assist in the diagnosis.

At present, genetic testing can be used to find out whether patients with inherited neurological diseases carry abnormal genes. The specificity and sensitivity of genetic testing can provide neurologists, psychiatrists, and geneticists with a reliable diagnostic tool.

Leopard Gene applies next-generation sequencing technology to examine the exons of the target gene for neurological diseases markers, and then analyze the hot spots related to disease-causing mutations to explore whether the patient has a potential risk of developing the disease, as a reference for clinical diagnosis, treatment and medication for physicians.

With the completion of the Human Genome Project and the rapid accumulation of big data on human diseases, scientists have decrypted the core secrets of human beings and discovered the sequence variations through genetic comparisons between healthy people and patients. At present, scientists are able to conduct early diagnosis and even predict the disease outcome through genetic testing and provide medication guidance based on the detection of abnormal gene sequence in the body.

In recent years, with the increase in the aging population, the number of chronic disease patients has also increased year by year, and countries all over the world have aggressively promoted the development of precision medicine. Since the completion of the human genome map in 2003, genetic medicine has carried endless hope. Genetic medicine as an epoch-making weapon for human race to defeat major and deadly diseases will accelerate in the 21st century.

The fight against the epidemic involves the strengthening of the health situation of the whole family. The selection of excellent strains by the doctoral team contains 7 probiotics each containing 20 billion bacteria.

Features

• Maintain the function of the digestive tract and make defecation smooth.
• Strict inspection and safety guaranteed.
• High quality and carefully selected nutritional supplements.